Assay Detail
Binding
CHEMBL4381880
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Nav1.2/Nav1.4 (unknown origin) expressed in Xenopus laevis oocytes at -80 mV holding potential by two electrode voltage-clamp assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structure and Activity Studies of Disulfide-Deficient Analogues of αO-Conotoxin GeXIVA.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.39 | 6.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2402969 | — | — | 1 | 6.34 |
| CHEMBL4530214 | — | — | 1 | 5.08 |
| CHEMBL4556625 | — | — | 1 | 4.76 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2402969 | — | IC50 | = | 460.0 | nM | 6.34 |
| CHEMBL4530214 | — | IC50 | = | 8240.0 | nM | 5.08 |
| CHEMBL4556625 | — | IC50 | = | 17370.0 | nM | 4.76 |