Assay Detail
Binding
CHEMBL4383865
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Inhibition of human trypsin preincubated for 30 mins followed by substrate addition and measured for 20 mins
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Design, synthesis and biological evaluation of anthranilamide derivatives as potential factor Xa (fXa) inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.69 | 8.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4441346 | — | — | 1 | 8.04 |
| CHEMBL4469752 | — | — | 1 | 7.75 |
| CHEMBL4469308 | — | — | 1 | 7.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4441346 | — | IC50 | = | 9.1 | nM | 8.04 |
| CHEMBL4469752 | — | IC50 | = | 18.0 | nM | 7.75 |
| CHEMBL4469308 | — | IC50 | = | 54.0 | nM | 7.27 |