Assay Detail
Functional
CHEMBL4385019
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Cytotoxicity against human AZ-521 cells assessed as reduction in cell viability after 48 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | AZ-521 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Melanogenesis-Inhibitory and Cytotoxic Activities of Triterpene Glycoside Constituents from the Bark of Albizia procera.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.12 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4451985 | — | — | 1 | 6.40 |
| CHEMBL4483588 | — | — | 1 | 6.30 |
| CHEMBL4581280 | — | — | 1 | 6.22 |
| CHEMBL4448517 | — | — | 1 | 5.92 |
| CHEMBL4561300 | — | — | 1 | 5.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4451985 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL4483588 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL4581280 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL4448517 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL4561300 | — | IC50 | = | 1700.0 | nM | 5.77 |