Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4385245

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human A549 cells after 48 hrs by XTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type A549
Confidence 1 — Organism
Curated By Autocuration

Target

A549 (CHEMBL392)
Type CELL-LINE
Organism Homo sapiens

Publication

NQO1-Selective Activated Prodrug of Triptolide: Synthesis and Antihepatocellular Carcinoma Activity Evaluation.
Liu M, Song W, Du X, Su J, Dong K, Chen Y, Peng Z.
ACS Med Chem Lett (2018) 9 : 1253 -1257
PubMed 30613335 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.23 7.23

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4473066 1 7.23

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4473066 IC50 = 59.4 nM 7.23