Assay Detail
Binding
CHEMBL4385442
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Substrate activity at NTR1 in promastigote stage of Leishmania donovani MHOM/SD/62/1S-CL2D assessed as inhibition of parasite growth after 72 hrs by resazurin dye based assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Leishmania donovani |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Nongenotoxic 3-Nitroimidazo[1,2-<i>a</i>]pyridines Are NTR1 Substrates That Display Potent <i>in Vitro</i> Antileishmanial Activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.29 | 7.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4534157 | — | — | 1 | 7.48 |
| CHEMBL4529002 | — | — | 1 | 7.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4534157 | — | IC50 | = | 33.0 | nM | 7.48 |
| CHEMBL4529002 | — | IC50 | = | 80.0 | nM | 7.10 |