Assay Detail
Binding
CHEMBL4386573
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant Escherichia coli EO516 N-terminal His-tagged CTX-M15 expressed in Escherichia coli BL21(DE3) assessed as residual enzyme activity using FC5 as substrate pre-incubated for 0 to 360 mins followed by substrate addition by fluorescence method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Profiling interactions of vaborbactam with metallo-β-lactamases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.89 | 7.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4533632 | — | — | 1 | 7.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4533632 | — | IC50 | = | 13.0 | nM | 7.89 |