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Assay Detail

CHEMBL4386618

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of catalytic activity of ppGalNAcT13 (unknown origin) using EA2 peptide as substrate incubated for 30 mins by HPLC-based enzyme assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Polypeptide N-acetylgalactosaminyltransferase 13 (CHEMBL4523392)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Inhibition of polypeptide N-acetyl-α-galactosaminyltransferases is an underlying mechanism of dietary polyphenols preventing colorectal tumorigenesis.
Liu F, Cui Y, Yang F, Xu Z, Da LT, Zhang Y.
Bioorg Med Chem (2019) 27 : 3372 -3382
PubMed 31227364 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.86 4.86

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL6338 1 4.86

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL6338 IC50 = 13780.0 nM 4.86