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Assay Detail

CHEMBL4386977

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human RAD51
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

DNA repair protein RAD51 homolog 1 (CHEMBL2034807)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Styryl quinazolinones and its ethynyl derivatives induce myeloid differentiation.
Radhakrishnan S, Syed R, Takei H, Kobayashi IS, Nakamura E, Sultana F, Kamal A, Tenen DG, Kobayashi SS.
Bioorg Med Chem Lett (2019) 29 : 2286 -2289
PubMed 31278031 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.22 5.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1567670 1 5.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1567670 IC50 = 6000.0 nM 5.22