Assay Detail
Functional
CHEMBL4388784
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Cytotoxicity against human SK-MEL-25 cells assessed as decrease in cell viability incubated for 24 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SK-MEL-25 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Capsaicin-like analogue induced selective apoptosis in A2058 melanoma cells: Design, synthesis and molecular modeling.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.07 | 4.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4527122 | — | — | 1 | 4.17 |
| CHEMBL4459363 | — | — | 1 | 4.04 |
| CHEMBL4538916 | — | — | 1 | 4.04 |
| CHEMBL4534595 | — | — | 1 | 4.01 |
| CHEMBL294199 | CAPSAICIN | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4527122 | — | IC50 | = | 67190.0 | nM | 4.17 |
| CHEMBL4459363 | — | IC50 | = | 91800.0 | nM | 4.04 |
| CHEMBL4538916 | — | IC50 | = | 90500.0 | nM | 4.04 |
| CHEMBL4534595 | — | IC50 | = | 98700.0 | nM | 4.01 |
| CHEMBL294199 | CAPSAICIN | IC50 | > | 100000.0 | nM | - |