Assay Detail
Binding
CHEMBL4390414
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]5-CT from human 5HT7 receptor expressed in in COS7 cells incubated for 30 mins by liquid scintillation counting method
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design, synthesis and molecular modelling of new bulky Fananserin derivatives with altered pharmacological profile as potential antidepressants.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 7.76 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL428494 | — | — | 1 | 8.70 |
| CHEMBL12702 | — | — | 1 | 8.30 |
| CHEMBL307101 | — | — | 1 | 7.92 |
| CHEMBL71390 | — | — | 1 | 7.70 |
| CHEMBL69388 | — | — | 1 | 7.13 |
| CHEMBL302723 | — | — | 1 | 6.83 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL428494 | — | Ki | = | 2.0 | nM | 8.70 |
| CHEMBL12702 | — | Ki | = | 5.0 | nM | 8.30 |
| CHEMBL307101 | — | Ki | = | 12.0 | nM | 7.92 |
| CHEMBL71390 | — | Ki | = | 20.0 | nM | 7.70 |
| CHEMBL69388 | — | Ki | = | 74.0 | nM | 7.13 |
| CHEMBL302723 | — | Ki | = | 147.0 | nM | 6.83 |