Assay Detail
Functional
CHEMBL4391029
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Antileishmanial activity against Leishmania major amastigotes
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania major |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel prenyloxy chalcones as potential leishmanicidal and trypanocidal agents: Design, synthesis and evaluation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.85 | 5.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4463525 | — | — | 1 | 5.85 |
| CHEMBL3601621 | — | — | 1 | 5.85 |
| CHEMBL4442681 | — | — | 1 | 5.85 |
| CHEMBL4483655 | — | — | 1 | 5.85 |
| CHEMBL3601623 | — | — | 1 | 5.85 |
| CHEMBL3601622 | — | — | 1 | 5.85 |
| CHEMBL3601624 | — | — | 1 | 5.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4463525 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL3601621 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL4442681 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL4483655 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL3601623 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL3601622 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL3601624 | — | IC50 | = | 1400.0 | nM | 5.85 |