Assay Detail
Functional
CHEMBL4391692
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Cytotoxicity against human K562 cells assessed as reduction in cell growth measured after 72 hrs by MTS assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | K562 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
N,N-bis-heteroaryl methylamines: Potent anti-mitotic and highly cytotoxic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 9.14 | 9.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4458738 | — | — | 1 | 9.22 |
| CHEMBL4439731 | — | — | 1 | 9.11 |
| CHEMBL498271 | — | — | 1 | 9.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4458738 | — | IC50 | = | 0.6 | nM | 9.22 |
| CHEMBL4439731 | — | IC50 | = | 0.77 | nM | 9.11 |
| CHEMBL498271 | — | IC50 | = | 0.8 | nM | 9.10 |