Assay Detail
Functional
CHEMBL4391693
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Cytotoxicity against human K562R cells assessed as reduction in cell growth measured after 72 hrs by MTS assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | K-562R |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
N,N-bis-heteroaryl methylamines: Potent anti-mitotic and highly cytotoxic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 9.09 | 9.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4458738 | — | — | 1 | 9.55 |
| CHEMBL498271 | — | — | 1 | 8.96 |
| CHEMBL4439731 | — | — | 1 | 8.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4458738 | — | IC50 | = | 0.28 | nM | 9.55 |
| CHEMBL498271 | — | IC50 | = | 1.1 | nM | 8.96 |
| CHEMBL4439731 | — | IC50 | = | 1.77 | nM | 8.75 |