Assay Detail
Functional
CHEMBL4392622
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Cytotoxicity against human MIAPaCa2 cells assessed as reduction in cell viability resazurin reagent based fluorescent assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MIA PaCa-2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
New analogs of SYA013 as sigma-2 ligands with anticancer activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.23 | 5.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4566049 | — | — | 1 | 5.82 |
| CHEMBL476108 | — | — | 1 | 5.70 |
| CHEMBL4467840 | — | — | 1 | 5.00 |
| CHEMBL4558031 | — | — | 1 | 4.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4566049 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL476108 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL4467840 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL4558031 | — | IC50 | = | 42000.0 | nM | 4.38 |