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Assay Detail

CHEMBL4393368

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antioxidant activity assessed as DPPH radical scavenging activity incubated for 15 to 20 mins by UV-visible spectrometry
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Publication

Cu-mediated synthesis of differentially substituted diazepines as AChE inhibitors; validation through molecular docking and Lipinski's filter to develop novel anti-neurodegenerative drugs.
Sudhapriya N, Manikandan A, Kumar MR, Perumal PT.
Bioorg Med Chem Lett (2019) 29 : 1308 -1312
PubMed 30956014 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 6.66 7.06

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4519496 1 7.06
CHEMBL4554996 1 7.02
CHEMBL196 ASCORBIC ACID 4.0 1 5.90

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4519496 IC50 = 86.25 nM 7.06
CHEMBL4554996 IC50 = 94.85 nM 7.02
CHEMBL196 ASCORBIC ACID IC50 = 1250.0 nM 5.90