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Assay Detail

CHEMBL4393779

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of PI3K in human lung parenchyma cells assessed as reduction in IL2 secretion
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Class 1 PI3K Clinical Candidates and Recent Inhibitor Design Strategies: A Medicinal Chemistry Perspective.
Garces AE, Stocks MJ.
J Med Chem (2019) 62 : 4815 -4850
PubMed 30582807 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.50 8.50

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4434674 1 8.50

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4434674 IC50 = 3.162 nM 8.50