Assay Detail
Functional
CHEMBL4393881
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Antileishmanial activity against promastigote stage of Leishmania infantum MHOM/PT/88/IMT151 as parasite growth inhibition after 48 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania infantum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Evaluation of synthetic substituted 1,2-dioxanes as novel agents against human leishmaniasis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.25 | 5.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4593142 | — | — | 1 | 5.46 |
| CHEMBL190579 | — | — | 1 | 5.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4593142 | — | IC50 | = | 3510.0 | nM | 5.46 |
| CHEMBL190579 | — | IC50 | = | 9350.0 | nM | 5.03 |