Assay Detail
Functional
CHEMBL4395239
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Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.56 | 4.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL54 | HALOPERIDOL | 4.0 | 1 | 4.70 |
| CHEMBL4564017 | — | — | 1 | 4.69 |
| CHEMBL4441396 | — | — | 1 | 4.55 |
| CHEMBL1215855 | — | — | 1 | 4.53 |
| CHEMBL4590308 | — | — | 1 | 4.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL54 | HALOPERIDOL | IC50 | = | 20170.0 | nM | 4.70 |
| CHEMBL4564017 | — | IC50 | = | 20530.0 | nM | 4.69 |
| CHEMBL4441396 | — | IC50 | = | 27830.0 | nM | 4.55 |
| CHEMBL1215855 | — | IC50 | = | 29600.0 | nM | 4.53 |
| CHEMBL4590308 | — | IC50 | = | 44750.0 | nM | 4.35 |