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Assay Detail

CHEMBL4395516

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of fluorescently labeled tracer binding to human ERG by competitive binding assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Publication

Ligand retargeting by binding site analogy.
Wiedmer L, Schärer C, Spiliotopoulos D, Hürzeler M, Śledź P, Caflisch A.
Eur J Med Chem (2019) 175 : 107 -113
PubMed 31077996 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.11 8.11

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL327980 1 8.11

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL327980 IC50 = 7.82 nM 8.11