Assay Detail
ADMET
CHEMBL4396485
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Cytotoxicity against human MCF7 cells measured after 96 hrs by SRB assay
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Caffeic acid phenethyl ester (CAPE)-derivatives act as selective inhibitors of acetylcholinesterase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 4.86 | 4.92 |
| Activity | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL319244 | CAFFEIC ACID PHENETHYL ESTER | — | 1 | 4.92 |
| CHEMBL133642 | — | — | 1 | 4.79 |
| CHEMBL4453275 | — | — | 1 | - |
| CHEMBL4465285 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL319244 | CAFFEIC ACID PHENETHYL ESTER | EC50 | = | 12100.0 | nM | 4.92 |
| CHEMBL133642 | — | EC50 | = | 16200.0 | nM | 4.79 |
| CHEMBL4453275 | — | Activity | - | — | - | |
| CHEMBL4465285 | — | Activity | - | — | - |