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Assay Detail

CHEMBL4396995

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to VHL (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

von Hippel-Lindau disease tumor suppressor (CHEMBL3108660)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Small-Molecule Modulators of the Hypoxia-Inducible Factor Pathway: Development and Therapeutic Applications.
Li Z, You Q, Zhang X.
J Med Chem (2019) 62 : 5725 -5749
PubMed 30682255 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 7.05 7.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4225537 1 7.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4225537 Kd = 90.0 nM 7.05