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Assay Detail

CHEMBL4397305

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Helix pomatia beta-mannosidase assessed as residual hydrolytic activity after 10 to 30 mins by spectrophotometric analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Helix pomatia
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Pharmacological Chaperones for the Treatment of α-Mannosidosis.
Rísquez-Cuadro R, Matsumoto R, Ortega-Caballero F, Nanba E, Higaki K, García Fernández JM, Ortiz Mellet C.
J Med Chem (2019) 62 : 5832 -5843
PubMed 31017416 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 4.70 4.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4483772 1 4.70
CHEMBL4471561 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4483772 Ki = 20000.0 nM 4.70
CHEMBL4471561 Ki - -