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Assay Detail

CHEMBL4398307

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Functional
Antiviral activity against DENV2 infected in BHK-21 cells assessed as viral replication
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism dengue virus type 2
Confidence 1 — Organism
Curated By Autocuration

Target

dengue virus type 2 (CHEMBL613966)
Type ORGANISM
Organism dengue virus type 2

Publication

Recent update on anti-dengue drug discovery.
Dighe SN, Ekwudu O, Dua K, Chellappan DK, Katavic PL, Collet TA.
Eur J Med Chem (2019) 176 : 431 -455
PubMed 31128447 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 5.40 5.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1324 TOLCAPONE 4.0 1 5.64
CHEMBL1458891 1 5.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1324 TOLCAPONE EC50 = 2290.0 nM 5.64
CHEMBL1458891 EC50 = 6900.0 nM 5.16