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Assay Detail

CHEMBL4398339

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Functional
Antiviral activity against DENV2 infected in HEK293 cells assessed as reduction in plaque formation
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism dengue virus type 2
Confidence 1 — Organism
Curated By Autocuration

Target

dengue virus type 2 (CHEMBL613966)
Type ORGANISM
Organism dengue virus type 2

Publication

Recent update on anti-dengue drug discovery.
Dighe SN, Ekwudu O, Dua K, Chellappan DK, Katavic PL, Collet TA.
Eur J Med Chem (2019) 176 : 431 -455
PubMed 31128447 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.07 6.07

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1720448 1 6.07

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1720448 EC50 = 850.0 nM 6.07