Assay Detail
Functional
CHEMBL4398356
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Antiviral activity against DENV2 infected in human Huh-7 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | dengue virus type 2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent update on anti-dengue drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.40 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1221911 | LACTIMIDOMYCIN | — | 1 | 6.40 |
| CHEMBL4547425 | — | — | 1 | - |
| CHEMBL4454264 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1221911 | LACTIMIDOMYCIN | EC50 | = | 400.0 | nM | 6.40 |
| CHEMBL4547425 | — | EC50 | = | 4.1 | ug.mL-1 | - |
| CHEMBL4454264 | — | EC50 | = | 3.5 | ug.mL-1 | - |