Assay Detail
Binding
CHEMBL4398434
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human placental microsome aromatase using [1beta[3H]]androst-4-ene-3,17-dione as substrate after 15 mins in presence of NADPH by liquid scintillation counting method
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Tissue | Placenta |
| Subcellular | Microsome |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Estrogen signaling: An emanating therapeutic target for breast cancer treatment.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 6.66 | 6.66 |
| IC50 | 1 | 6.68 | 6.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL188664 | — | — | 2 | 6.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL188664 | — | IC50 | = | 210.0 | nM | 6.68 |
| CHEMBL188664 | — | Ki | = | 220.0 | nM | 6.66 |