Assay Detail
Binding
CHEMBL4399065
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition G9a (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Histone-lysine N-methyltransferase EHMT2 (CHEMBL6032) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Recent progress in histone methyltransferase (G9a) inhibitors as anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.85 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1231795 | — | — | 1 | 7.82 |
| CHEMBL3414617 | — | — | 1 | 5.20 |
| CHEMBL4435238 | — | — | 1 | 4.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1231795 | — | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL3414617 | — | IC50 | = | 6300.0 | nM | 5.20 |
| CHEMBL4435238 | — | IC50 | = | 30100.0 | nM | 4.52 |