Assay Detail
Binding
CHEMBL4399449
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Inhibition of human HLE
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Applications of amide isosteres in medicinal chemistry.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.68 | 8.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL11391 | — | — | 1 | 8.35 |
| CHEMBL428848 | — | — | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL11391 | — | Ki | = | 4.5 | nM | 8.35 |
| CHEMBL428848 | — | Ki | = | 101.0 | nM | 7.00 |