Assay Detail
Binding
CHEMBL4401315
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant HDAC3/GST-tagged NCOR1 DAD (397 to 503 residues) expressed in baculovirus expression system by fluorescence assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Histone deacetylase 3 inhibitors in learning and memory processes with special emphasis on benzamides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.60 | 6.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3622374 | — | — | 1 | 6.62 |
| CHEMBL3622375 | — | — | 1 | 6.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3622374 | — | IC50 | = | 240.0 | nM | 6.62 |
| CHEMBL3622375 | — | IC50 | = | 260.0 | nM | 6.58 |