Assay Detail
Functional
CHEMBL4403204
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Cytotoxicity against human C8166 cells assessed as reduction in cell viability
7
Total Activities
7
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | C8166 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthetic routes and structure-activity relationships (SAR) of anti-HIV agents: A key review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | - | - |
| EC50 | 3 | 7.15 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1643090 | — | — | 1 | 7.16 |
| CHEMBL1643092 | — | — | 1 | 7.16 |
| CHEMBL1643094 | — | — | 1 | 7.12 |
| CHEMBL4548996 | — | — | 1 | - |
| CHEMBL4540163 | — | — | 1 | - |
| CHEMBL4435518 | — | — | 1 | - |
| CHEMBL129 | ZIDOVUDINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1643090 | — | EC50 | = | 69.81 | nM | 7.16 |
| CHEMBL1643092 | — | EC50 | = | 69.81 | nM | 7.16 |
| CHEMBL1643094 | — | EC50 | = | 75.78 | nM | 7.12 |
| CHEMBL4548996 | — | IC50 | = | 83.21 | ug.mL-1 | - |
| CHEMBL4540163 | — | IC50 | = | 114.33 | ug.mL-1 | - |
| CHEMBL4435518 | — | IC50 | = | 97.51 | ug.mL-1 | - |
| CHEMBL129 | ZIDOVUDINE | IC50 | = | 1565.72 | ug.mL-1 | - |