Assay Detail
Functional
CHEMBL4403364
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antileishmanial activity against Leishmania amazonensis MHOM/BR/75/Josefa intracellular amastigotes infected in CF-1 macrophages assessed as reduction in parasite viability after 72 hrs by optical microscopic method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania amazonensis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Multi-target drugs active against leishmaniasis: A paradigm of drug repurposing.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.10 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL64391 | ITRACONAZOLE | 4.0 | 1 | 7.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL64391 | ITRACONAZOLE | IC50 | = | 80.0 | nM | 7.10 |