Assay Detail
Binding
CHEMBL4403385
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Inhibition of 20S proteasome beta 2c (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Immunoproteasome-selective inhibitors: An overview of recent developments as potential drugs for hematologic malignancies and autoimmune diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.51 | 7.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4465456 | — | — | 1 | 7.09 |
| CHEMBL4443505 | — | — | 1 | 5.93 |
| CHEMBL4441524 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4465456 | — | IC50 | = | 81.0 | nM | 7.09 |
| CHEMBL4443505 | — | IC50 | = | 1176.0 | nM | 5.93 |
| CHEMBL4441524 | — | IC50 | > | 25000.0 | nM | - |