Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4403391

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiparasitic activity against Plasmodium falciparum W2
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

New dimensions in the field of antimalarial research against malaria resurgence.
Narula AK, Azad CS, Nainwal LM.
Eur J Med Chem (2019) 181 : 111353 -111353
PubMed 31525705 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 13 8.08 8.87

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3264503 1 8.87
CHEMBL3264171 1 8.58
CHEMBL3264174 1 8.58
CHEMBL3264178 1 8.58
CHEMBL3264179 1 8.58
CHEMBL3264183 1 8.58
CHEMBL3264190 1 8.58
CHEMBL3264192 1 8.58
CHEMBL3264501 1 8.43
CHEMBL4555605 1 6.95
CHEMBL4446072 1 6.43
CHEMBL76 CHLOROQUINE 4.0 1 6.16
CHEMBL197308 FERRUGINOL 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3264503 IC50 = 1.35 nM 8.87
CHEMBL3264171 IC50 = 2.63 nM 8.58
CHEMBL3264174 IC50 = 2.63 nM 8.58
CHEMBL3264178 IC50 = 2.63 nM 8.58
CHEMBL3264179 IC50 = 2.63 nM 8.58
CHEMBL3264183 IC50 = 2.63 nM 8.58
CHEMBL3264190 IC50 = 2.63 nM 8.58
CHEMBL3264192 IC50 = 2.63 nM 8.58
CHEMBL3264501 IC50 = 3.74 nM 8.43
CHEMBL4555605 IC50 = 112.5 nM 6.95
CHEMBL4446072 IC50 = 370.0 nM 6.43
CHEMBL76 CHLOROQUINE IC50 = 697.94 nM 6.16
CHEMBL197308 FERRUGINOL IC50 = 0.9 ug.mL-1 -