Assay Detail
Functional
CHEMBL4403398
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Antiparasitic activity against Plasmodium falciparum 3D7
11
Total Activities
11
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
New dimensions in the field of antimalarial research against malaria resurgence.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 6.70 | 7.71 |
| EC50 | 2 | 8.70 | 8.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2431810 | — | — | 1 | 8.89 |
| CHEMBL3361390 | — | — | 1 | 8.50 |
| CHEMBL4521552 | — | — | 1 | 7.71 |
| CHEMBL4471833 | — | — | 1 | 7.71 |
| CHEMBL4446072 | — | — | 1 | 7.54 |
| CHEMBL4552108 | — | — | 1 | 6.22 |
| CHEMBL4469250 | — | — | 1 | 6.22 |
| CHEMBL4441848 | — | — | 1 | 6.22 |
| CHEMBL4538914 | — | — | 1 | 6.22 |
| CHEMBL4587779 | — | — | 1 | 6.22 |
| CHEMBL4463515 | — | — | 1 | 6.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2431810 | — | EC50 | = | 1.3 | nM | 8.89 |
| CHEMBL3361390 | — | EC50 | = | 3.18 | nM | 8.50 |
| CHEMBL4521552 | — | IC50 | = | 19.69 | nM | 7.71 |
| CHEMBL4471833 | — | IC50 | = | 19.69 | nM | 7.71 |
| CHEMBL4446072 | — | IC50 | = | 29.0 | nM | 7.54 |
| CHEMBL4552108 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL4469250 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL4441848 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL4538914 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL4587779 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL4463515 | — | IC50 | = | 600.0 | nM | 6.22 |