Assay Detail
Functional
CHEMBL4403436
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human PC3 cells assessed as reduction in cell viability
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent advances in α,β-unsaturated carbonyl compounds as mitochondrial toxins.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.09 | 5.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL317469 | — | — | 1 | 5.09 |
| CHEMBL105310 | 2',4'-DIHYDROXYCHALCONE | — | 1 | 5.09 |
| CHEMBL4514458 | — | — | 1 | 5.09 |
| CHEMBL4537198 | — | — | 1 | 5.09 |
| CHEMBL4447825 | — | — | 1 | 5.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL317469 | — | IC50 | = | 8080.0 | nM | 5.09 |
| CHEMBL105310 | 2',4'-DIHYDROXYCHALCONE | IC50 | = | 8080.0 | nM | 5.09 |
| CHEMBL4514458 | — | IC50 | = | 8080.0 | nM | 5.09 |
| CHEMBL4537198 | — | IC50 | = | 8080.0 | nM | 5.09 |
| CHEMBL4447825 | — | IC50 | = | 8080.0 | nM | 5.09 |