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Assay Detail

CHEMBL4403511

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Functional
Antiparasitic activity against Toxoplasma gondii infected in human HFF cells after 4 hrs by CellTiter 96Aqueous One cell viability assay
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Toxoplasma gondii
Confidence 1 — Organism
Curated By Autocuration

Target

Toxoplasma gondii (CHEMBL612888)
Type ORGANISM
Organism Toxoplasma gondii

Publication

Recent progress on anti-Toxoplasma drugs discovery: Design, synthesis and screening.
Deng Y, Wu T, Zhai SQ, Li CH.
Eur J Med Chem (2019) 183 : 111711 -111711
PubMed 31585276 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 8.30 8.30
IC50 2 9.00 9.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2030049 1 9.00
CHEMBL3637903 1 8.30
CHEMBL4529042 1 -
CHEMBL3261731 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2030049 IC50 = 1.0 nM 9.00
CHEMBL3637903 EC50 = 5.0 nM 8.30
CHEMBL4529042 EC50 = 0.003 nM -
CHEMBL3261731 IC50 = 0.007 nM -