Assay Detail
Functional
CHEMBL4403515
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Antiparasitic activity against Toxoplasma gondii infected in human HFF cells after 7 days by crystal violet assay
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Toxoplasma gondii |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent progress on anti-Toxoplasma drugs discovery: Design, synthesis and screening.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.96 | 5.70 |
| EC50 | 1 | 7.52 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL257166 | JASPAMIDE | — | 1 | 7.52 |
| CHEMBL4568326 | — | — | 1 | 5.70 |
| CHEMBL28079 | ZAPRINAST | 2.0 | 1 | 4.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL257166 | JASPAMIDE | EC50 | = | 30.0 | nM | 7.52 |
| CHEMBL4568326 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL28079 | ZAPRINAST | IC50 | = | 60000.0 | nM | 4.22 |