Assay Detail
Functional
CHEMBL4403516
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Antiparasitic activity against Toxoplasma gondii RH infected in human HFF cells in presence of [3H]acetate by radio-labelled assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Toxoplasma gondii |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent progress on anti-Toxoplasma drugs discovery: Design, synthesis and screening.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 7.43 | 8.01 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4527690 | — | — | 1 | 8.01 |
| CHEMBL4441015 | — | — | 1 | 7.99 |
| CHEMBL4551199 | — | — | 1 | 7.95 |
| CHEMBL445599 | — | — | 1 | 5.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4527690 | — | EC50 | = | 9.7 | nM | 8.01 |
| CHEMBL4441015 | — | EC50 | = | 10.2 | nM | 7.99 |
| CHEMBL4551199 | — | EC50 | = | 11.3 | nM | 7.95 |
| CHEMBL445599 | — | EC50 | = | 1800.0 | nM | 5.75 |