Assay Detail
Functional
CHEMBL4403520
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Antiparasitic activity against Toxoplasma gondii infected in human HFF cells after 4 hrs
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Toxoplasma gondii |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent progress on anti-Toxoplasma drugs discovery: Design, synthesis and screening.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.34 | 6.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4525036 | — | — | 1 | 6.89 |
| CHEMBL4571126 | — | — | 1 | 6.70 |
| CHEMBL591128 | — | — | 1 | 6.57 |
| CHEMBL601497 | — | — | 1 | 5.89 |
| CHEMBL527577 | — | — | 1 | 5.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4525036 | — | IC50 | = | 130.0 | nM | 6.89 |
| CHEMBL4571126 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL591128 | — | IC50 | = | 270.0 | nM | 6.57 |
| CHEMBL601497 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL527577 | — | IC50 | = | 2300.0 | nM | 5.64 |