Assay Detail
Binding
CHEMBL4403586
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Agonist activity at AgrC-3 in Staphylococcus aureus incubated for 60 to 90 mins in presence of AIP agonist by beta-lactamase reporter gene assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Staphylococcus aureus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structure-Activity Relationship Studies of Small Molecule Modulators of the Staphylococcal Accessory Gene Regulator.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.84 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3289785 | — | — | 1 | 9.00 |
| CHEMBL4442959 | — | — | 1 | 9.00 |
| CHEMBL2337554 | — | — | 1 | 8.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3289785 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL4442959 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL2337554 | — | IC50 | = | 3.0 | nM | 8.52 |