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Assay Detail

CHEMBL4403650

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human NCI-H1299 cells incubated for 2 days followed by medium replacement by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type NCI-H1299
Confidence 1 — Organism
Curated By Autocuration

Target

NCI-H1299 (CHEMBL612255)
Type CELL-LINE
Organism Homo sapiens

Publication

Heat Shock Protein 90 Inhibitors: An Update on Achievements, Challenges, and Future Directions.
Li L, Wang L, You QD, Xu XL.
J Med Chem (2020) 63 : 1798 -1822
PubMed 31663736 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.85 6.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2177146 1 6.85

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2177146 IC50 = 140.0 nM 6.85