Assay Detail
Binding
CHEMBL4403728
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Displacement of [3H]-flumazenil from human GABAA alpha2beta3gamma2 expressed in Ltk cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Subtype Selective γ-Aminobutyric Acid Type A Receptor (GABA<sub>A</sub>R) Modulators Acting at the Benzodiazepine Binding Site: An Update.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 9.29 | 9.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4303594 | — | — | 1 | 9.40 |
| CHEMBL373250 | — | — | 1 | 9.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4303594 | — | Ki | = | 0.4 | nM | 9.40 |
| CHEMBL373250 | — | Ki | = | 0.67 | nM | 9.17 |