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Assay Detail

CHEMBL4403791

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of HIV-1 protease by spectrofluorometric assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Human immunodeficiency virus 1
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Protease (CHEMBL2366517)
Type SINGLE PROTEIN
Organism Human immunodeficiency virus 1

Publication

Urea Derivatives in Modern Drug Discovery and Medicinal Chemistry.
Ghosh AK, Brindisi M.
J Med Chem (2020) 63 : 2751 -2788
PubMed 31789518 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.20 8.20

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL322241 TELINAVIR 2.0 1 8.20

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL322241 TELINAVIR IC50 = 6.3 nM 8.20