Assay Detail
Binding
CHEMBL4404012
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Inhibition of human erythrocyte Glyoxalase-1
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent advances in the discovery and development of glyoxalase I inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.33 | 7.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL128872 | — | — | 1 | 7.85 |
| CHEMBL131578 | — | — | 1 | 7.34 |
| CHEMBL128935 | — | — | 1 | 6.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL128872 | — | Ki | = | 14.0 | nM | 7.85 |
| CHEMBL131578 | — | Ki | = | 46.0 | nM | 7.34 |
| CHEMBL128935 | — | Ki | = | 160.0 | nM | 6.80 |