Assay Detail
Binding
CHEMBL4404237
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Inhibition of porcine cerebellar microsomes SERCA2b by enzyme-coupled method
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa domesticus |
| Tissue | Cerebellum |
| Subcellular | Microsomes |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Sarco/Endoplasmic Reticulum Calcium ATPase Inhibitors: Beyond Anticancer Perspective.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.19 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL184450 | — | — | 1 | 6.30 |
| CHEMBL410063 | PAXILLINE | — | 1 | 5.30 |
| CHEMBL140 | CURCUMIN | 3.0 | 1 | 5.16 |
| CHEMBL560141 | — | — | 1 | 4.64 |
| CHEMBL2059712 | ALISOL B | — | 1 | 4.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL184450 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL410063 | PAXILLINE | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL140 | CURCUMIN | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL560141 | — | IC50 | = | 23000.0 | nM | 4.64 |
| CHEMBL2059712 | ALISOL B | IC50 | = | 27000.0 | nM | 4.57 |