Assay Detail
Binding
CHEMBL4404238
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Inhibition of SERCA2a (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (CHEMBL3901) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Sarco/Endoplasmic Reticulum Calcium ATPase Inhibitors: Beyond Anticancer Perspective.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.14 | 8.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4514624 | — | — | 1 | 8.89 |
| CHEMBL4207081 | — | — | 1 | 7.96 |
| CHEMBL4216774 | — | — | 1 | 7.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4514624 | — | Ki | = | 1.3 | nM | 8.89 |
| CHEMBL4207081 | — | Ki | = | 11.0 | nM | 7.96 |
| CHEMBL4216774 | — | Ki | = | 27.0 | nM | 7.57 |