Assay Detail

CHEMBL4404244

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Binding

Inhibition of SERCA in rat testicular microsomes

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Rattus norvegicus
Tissue	Testis
Subcellular	Microsomes
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Sarco/Endoplasmic Reticulum Calcium ATPase Inhibitors: Beyond Anticancer Perspective.

Peterková L, Kmoníčková E, Ruml T, Rimpelová S.
J Med Chem (2020) 63 : 1937 -1963
PubMed 32030976 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.46	6.46

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL153062	4-NONYLPHENOL	—	1	6.46

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL153062	4-NONYLPHENOL	IC50	=	350.0	nM	6.46