Assay Detail
Binding
CHEMBL4404249
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of SERCA3 in human platelet microsomes by enzyme-coupled method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (CHEMBL2401) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Sarco/Endoplasmic Reticulum Calcium ATPase Inhibitors: Beyond Anticancer Perspective.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.23 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL410063 | PAXILLINE | — | 1 | 5.30 |
| CHEMBL140 | CURCUMIN | 3.0 | 1 | 5.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL410063 | PAXILLINE | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL140 | CURCUMIN | IC50 | = | 7000.0 | nM | 5.16 |