Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4404876

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Agonist activity at rat FFA3 receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Free fatty acid receptor 3 (CHEMBL3886125)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Structure-Activity Relationship Studies of Tetrahydroquinolone Free Fatty Acid Receptor 3 Modulators.
Ulven ER, Quon T, Sergeev E, Barki N, Brvar M, Hudson BD, Dutta P, Hansen AH, Bielefeldt LØ, Tobin AB, McKenzie CJ, Milligan G, Ulven T.
J Med Chem (2020) 63 : 3577 -3595
PubMed 32141297 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 3 6.20 6.39

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4530642 1 6.39
CHEMBL4564389 1 6.34
CHEMBL4448591 1 5.87

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4530642 EC50 = 407.38 nM 6.39
CHEMBL4564389 EC50 = 457.09 nM 6.34
CHEMBL4448591 EC50 = 1348.96 nM 5.87