Assay Detail
Binding
CHEMBL4407028
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CDK4 (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
An overview on the synthetic and medicinal perspectives of indenopyrazoles.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 10.13 | 10.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL151546 | — | — | 1 | 10.59 |
| CHEMBL148580 | — | — | 1 | 10.10 |
| CHEMBL4453997 | — | — | 1 | 9.70 |
| CHEMBL334285 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL151546 | — | IC50 | = | 0.026 | nM | 10.59 |
| CHEMBL148580 | — | IC50 | = | 0.08 | nM | 10.10 |
| CHEMBL4453997 | — | IC50 | = | 0.2 | nM | 9.70 |
| CHEMBL334285 | — | IC50 | = | 0.007 | nM | - |